Vegicaps^® Capsules

Plant-derived technology for semi-solid compounds

Tailoring softgel technologies to the evolving needs of our customers, our innovation efforts have led us to develop an alternative to gelatin capsules. Vegicaps^® capsules are an easy-to-swallow, plant-based shell, free from animal derivatives, gluten, and modified sugars. As the innovators of softgel technology, we bring over 75 years of pharmaceutical and consumer health experience to softgel development, delivery, and supply. An optimal solution for semi-solid compounds and those with higher melting points, Vegicaps^® capsules can provide a solution to your drug development challenges.

Because they may be accepted by those with cultural and religious restrictions to animal-based products, Vegicaps^® capsules provide a catalyst for your entry into emerging markets. The plant-derived shell formulation offers the capability to handle a wider range of compounds, especially those with higher melting points.

Catalent Benefits 

• Handle compounds with higher melting points for fill formulation 
• Solve complex development and formulation challenges 
• Improve bioavailability of poorly water-soluble and poorly permeable compounds
• Enhance dose uniformity of your potent compounds
• Get specialized handling and manufacturing for your cytotoxic compounds
• Broader array of APIs filled into the softgel
  • Encapsulation of higher melting point fill formulations that are highly viscous or semi-solid at room temperatures as well as full formulation with higher pHs
• Stabile 
  • Enhanced stability for sensitive actives
• Safe
  • Tamper evident
• Reliable
  • More accurate dosing
• Wider market targeting
  • Targeting consumers adverse to eating animal-based products such as gelatin, following religious or cultural restrictions, or allergic to gluten
• Versatile
  • Variety of colors, shapes, sizes, and clarity 

Valuable Product Differentiation

• Plant-based shell free of all animal derivatives
• Easy to swallow
• Sugar and gluten free
• Low shell odor and non-distinguishing taste

Catalent Capabilities

We have a long track record of customizing successful programs involving our proprietary advanced technologies: 

• Preformulation and feasibility studies
• Solubility screening of NCEs
• Softgel capsule fill formulation development 
• Small-scale lab encapsulation for providing early stability data and final formulation selection 
• Shell development 
  • An extensive shell library, which enables us to offer a wide variety of options for a range of products 
  • A large range of shell formula possibilities and compatibility concerns
• Strong IP (intellectual property) positions including fill formulations for improved bioavailability
• Extensive technical support in softgel capsule product development
  • Self-emulsifying/microemulsion vehicle systems
  • Unique formulations leading to patentable line extensions 
• Reliable supply from clinical phases to commercial manufacturing
• Contingency planning and quality assurance via our large global network

Facilities

All of our sites are subject to annual review so we can remain in compliance with cGMP, FDA, EMA, and locally accreditation softgel facilities.