Quick Thinking: Fast Dissolve Formulations

Quick Thinking: Fast Dissolve Formulations

Authors: Rob Travers, Group Product Manager & Leon Grother, Principal Scientist

Summary: A detailed understanding of the material science of the tablet structure and how this relates to the desired tablet function is central to developing effective and commercially successful orally dispersing tablets. In the case of Zydis ODTs, freezedrying is not simply an effective means of water removal, but rather an effective processing tool that enables the production of tablets with a unique porous structure. The tablet porosity and carefully chosen carrier materials together produce tablets that typically disperse orally in less than three seconds and have a patient-preferred mouth feel and palatability.

Download to learn more about how Lyophilisation-based formulations are manufactured, the free-drying process and what patient populations are better served by using this unique finished dose type.

DOWNLOAD PDF