OptiGel® Mini Technology

Innovative Oral Softgel platform that delivers full strength APIs in a small, powerful softgel

As a leading innovator of softgel technology, we’ve developed the next generation in softgels that deliver the same full strength efficacy in a more preferred smaller dose.

Technical Advantages
  • Enables higher API concentrations into smaller capsules
  • Helps improve absorption and better permeability
  • Improved performance of compounds in lipophilic and hydrophilic formulations
  • Solutions to complex API formulation and development issues
  • Formulations in  single API and API combinations
  • Safe and tamper evident
Consumer Benefits
  • Highly concentrated formula provides full strength efficacy with reduced size
  • Approximately 30% smaller than traditional softgels for ease of use
  • Fast acting relief
  • Improves compliance, especially for seniors and children
  • Versatile softgel options available in variety of colors, shapes, sizes, and clarity 
Catalent Development Expertise
  • Preformulation and feasibility studies
  • Solubility screening of NCEs
  • Softgel capsule fill formulation development
  • Small-scale lab encapsulation for providing early stability data and final formulation selection
  • Shell development
    • An extensive shell library, which enables us to offer a wide variety of options for a range of products
    • A large range of shell formula possibilities and compatibility concerns
  • IP (intellectual property) positions including fill formulations for improved bioavailability
  • Extensive technical support in softgel capsule product development
    • Self-emulsifying/micro emulsion vehicle systems
    • Unique formulations potentially leading to patentable line extensions
  • Reliable supply from clinical phases to commercial manufacturing
  • Contingency planning and quality assurance via our large global network
Facilities

All of our sites are subject to annual review so we can remain in compliance with cGMP, FDA, EMA, and locally accredited softgel facilities.