Designing Optimized, Site-Specific ADCs

Summary: Antibody-drug conjugates have provided a breakthrough in targeted medicines but ways of increasing their stability and efficacy are still required. Historically, the technologies used to build these two approved products result in a heterogeneous milieu of conjugates. These mixtures of ADCs have been plagued with manufacturing challenges due to batch-to-batch variability and complicated analytics.Catalent highlights how these goals can be achieved using its technology platforms to produce site-specific ADCs.

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