Nanoparticulate Zydis®

Manufacture of Nanoparticulate Zydis® Fast-Dissolve Tablets using Fish Gelatin

Authors: D. Bahl, I. Vitez, K. Crowley

This study evaluated the use of fish gelatin to support nanoparticle formation of poorly water soluble drugs during wet milling and to maintain stable nanoparticulates in Zydis® fast-dissolving tablets manufactured by freeze-drying. The conclusion found that the Zydis® technology provides a viable approach for the oral delivery of nanoparticles.