Beyond Amorphous Solid Dispersion: Novel Applications in Pharmaceutical Spray Drying Executive Summary
Abstract: Spray drying has evolved beyond amorphous solid dispersions to become a scalable, versatile manufacturing platform for small molecules, peptides, biologics, and emerging modalities. This executive summary explores how advances in spray drying technology, modeling, automation, and process analytics are addressing long‑standing challenges in bioavailability, stability, and commercial scale‑up. Through real‑world examples and a focus on quality‑by‑design, simulation, and digitalization, the piece highlights how spray drying can accelerate development timelines, improve manufacturability, and support the transition to continuous pharmaceutical manufacturing.