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Particle Size Reduction Strategies to Improve Drug Performance

Summary: The ability to control and improve the dissolution rates of small molecule APIs is important when designing safe and effective oral dosage forms. In many cases, careful engineering of the particle size can give better bioavailability and, consequently, improved efficacy. Whether the target product is an inhaled medication or an oral dosage form, substantial improvements can often be made via the application of statistical and experimental design techniques. Read this article to learn how micronisation and nanosizing can be used to create market differentiation in a crowded therapeutic area, and enable products that meet the specific medical needs of individual patients to be introduced.

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