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Intranasal Drug Delivery: the Challenges and Opportunities

Summary: The intranasal delivery route is commonly used for the local treatment of allergic rhinitis and cold symptoms, but it is also recognized as an alternative systemic drug delivery route for a variety of indications, including migraine, seizures, breakthrough pain, and opioid overdose. In this article, experts discuss how the intranasal route offers advantages like faster absorption and minimal product degradation, but also the complex issues to consider when designing a device that will ensure the efficacy of a particular formulation.

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This article is taken from Pharmaceutical Manufacturing and Packing Sourcer May 2023, Inhalation Technology Supplement pages 22–24. © Samedan Ltd