Modern Modelling Tools for Small Molecule Solid Dose Manufacturing
Summary: Rising costs, evolving regulations, and technological advancements are all impacting the manufacture of pharmaceutical oral solid dosage forms. To remain competitive, companies must adopt efficient manufacturing practices that drive product innovation. As the pharmaceutical industry continues moving from batch towards continuous manufacturing, model-based approaches to process design and development, rather than empirical experimentation, offer the necessary insight to achieve product efficacy and manufacturing efficiency. This article explores current trends for OSD manufacturing and references real-world case studies to examine how mathematical and computerized modelling tools can improve scale-up and efficiency.