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Small Molecule Analytical Chemistry

ANALYTICAL TECHNIQUES & INSTRUMENTATION

LEADING ANALYTICAL SCIENTISTS WITH ADVANCED INSTRUMENTATION

We offer a wide range of small molecule analytical testing services including:

Chromatography

  • High Performance Liquid Chromatography (HPLC)
  • Ultra High Performance Liquid Chromatography (UHPLC)
  • Rapid Resolution Liquid Chromatography (RRLC)
  • Wide range of HPLC detectors – UV, PDA, Fluorescence, CAD, RI, ELSD
  • Chiral HPLCIon ChromatographyGas Chromatography (GC)
  • Thin Layer Chromatography (TLC)
  • Capillary Electrophoresis (CE)

CFR Part 11 Compliant Chromatography Data Acquisition System

Organic Spectroscopy

  • Nuclear Magnetic Resonance Spectroscopy (NMR)
  • Fourier Transform Infrared Spectrophotometry (FTIR)
  • UV/VIS SpectrophotometryPolarimetry
  • Near Infrared (NIR)
  • Raman Spectroscopy
  • Mass Spectrometry
  • X-Ray Powder Diffraction

Dissolution

  • USP Apparatus 1, 2, 3, 4, 5, 6, 7
  • F2 Testing
  • Biowaivers
  • Intrinsic Dissolution

Karl Fischer

  • Volumetric
  • Coulometric
  • Evaporative

Physical Testing

  • Hardness
  • Friability
  • Particulates (HIAC)
  • Osmolality/Osmolarity
  • Disintegration
  • Viscometers

Particle Analysis

  • Malvern
  • Microscopy
  • Sieving
  • HIAC
  • Cascade impaction

Thermal Analysis

  • Differential Scanning Calorimetry (DSC)
  • Thermogravimetric Analysis (TGA)
  • Dynamic Vapor Desorption (DVS)

Metals Analysis

  • Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
  • Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES/OES)
  • Microwave Digestion
  • Graphite Furnace Atomic Absorption Spectrometry (GFAAS)
  • Cold Vapor Atomic Absorption Spectrometry (CVAAS)
  • Flame Atomic Absorption Spectrometry (FAAS)

Microscopy

  • Light Microscopy
  • Hot Stage/Optical Microscopy
  • Cold Stage/Optical Microscopy

Pulmonary and Nasal

  • Blend/Content Uniformity
  • Dose through Life
  • Total Assay/Net Fill
  • Aerodynamic Particle Size (ACI, NGI)
  • Droplet Size, Particle Size
  • Spray Pattern
  • Plume Geometry
  • Zeta Potential

Microbiology

  • Antimicrobial Efficacy
  • Bioburden
  • Container Closure
  • Endotoxin
  • Microbial Limits (MLT)
  • Sterility
  • Microbial Identification

E-tongue

  • Bitterness Prediction
  • Taste Masking
  • Placebo Matching

Stability Storage & Testing