Developing Optimised Formulations with Minimal Drug Substance
Advances in in silico and experimental techniques mean that APIs and prototype formulations can be thoroughly characterised using multiple material-sparing assays, allowing the most promising formulation candidates to move on to in vivo studies.
Optimizing Oral Drug Delivery using Zydis® Orally Disintegrating Tablet Technology to Address Patient Challenges
This article looks at how innovation in the industry-leading Zydis ODT platform is expanding oral formulation options and bringing benefits to patients.
Using Zydis® ODT to Solve Delivery Challenges for Tolerogenic Vaccines
Summary: Using Zydis® orally dissolving tablet (ODT) platform from Catalent as a unique delivery route for allergy immunotherapies.
Biologics By Mouth-Leveraging Freeze-Dried Orally Disintegrating Tablets
Summary: Learn more about the role of oral dose delivery for tolerogenic vaccines, fast dissolving tablets and biological APIs.
Is My Molecule Suitable for an Orally Disintegrating Tablet?
Summary: While new drug products may benefit from ODT formulation beginning with product launch, ODT formulation can also play a role in life cycle management of approved products.
OptiForm® Solution Suite Bio Capabilities Sheet
OptiForm® Solution Suite Bio is designed to rapidly screen biomolecules’ potential for a non-invasive delivery route.
Exclusive Orphan Drugs Industry Survey Results Desire to Treat Rare Diseases Tempered by a Lack of Internal Expertise and Capability
Summary: Orphan drugs face obstacles that span from discovery to launch, largely because of small patient populations and limited markets for rare disease therapies.
Zydis® Orally Disintegrating Tablet (ODT) vs. Standard Tablets (ST)
Summary: This infographic provides a high level summary of studies comparing Zydis ODT against traditional oral tablets.
Is My Molecule Suitable for an Orally Disintegrating Tablet?
Summary: This webinar aims to provide clarity on the types of molecules suitable for an ODT format as well as the regulatory pathways for new and established therapies.
Amorphous and Co-Amorphous Systems for Poorly Soluble Drugs
Summary: This webinar provides an overview of co-amorphous research and its recent findings, particularly, the impact of low molecular weight excipient on developability, stability and solubility.
Getting Your Molecule From Preclinical Dev to Phase I
Summary: Three early drug development experts present insights and techniques to help your clients get their molecules from preclinical to Phase 1 studies.
Early Drug Development: Strategy and Solution
This webinar focuses on the key considerations for transitioning small molecules from preclinical through clinical development.
From Development to Commercialization: Overcoming Scale-Up Issues
Summary: Recorded at Manufacturing Chemist Live 2020, this presentation discusses some of the key issues to consider when planning for the scale-up of a small molecule development program.
Interview: Fierce Pharma with Jeremie Trochu
Summary: Jeremy Trochu, Vice President and General Manager of Pharmaceutical Development Services at Catalent, recently sat down for an interview…
OneXpress™: Phase Appropriate Technology & Expertise from Development to Commercialization
Summary: OneXpress is a single integrated solution that provides the fastest pathway from clinical development to commercial manufacturing. By taking a proactive approach and assessing production considerations early in development, our teams…
Early Phase Solutions
Summary: Explore how you can leverage Catalent’s successful track record optimizing thousands of molecules, deep development expertise and broadest set of superior technologies to…
Catalent Spray Drying Technology: From Development to Manufacturing
Summary: Catalent offers end-to-end spray drying solutions from early-phase development through to clinical supply, and scale-up to commercial finished dose forms.
Strategies to Avoid Dangerous Pitfalls in Pharmaceutical Consulting
Summary: Learn the strategies to avoid costly pitfalls in pharmaceutical consulting and Gain inside tips on using CDMO’s to deliver solutions to your clients.
Setting Up Your Small Molecule for Success: Formulation, PBPK Modeling and Regulatory Strategies in Early Clinical Trials
Summary: This webinar focuses on the key considerations for transitioning small molecules from preclinical through clinical development.
CMC Considerations for Successful Early Drug Development
Summary: This eBook provides insights on key approaches and considerations for preparing your drug development program for long-term success.
Phase Appropriate Expertise and Technologies to Accelerate Product Development to Commercialization
Summary: In this webinar, pharmaceutical scientists present real-life examples of challenges they’ve overcome in the transfer of oral small molecules from early-phase development to late-phase manufacturing.
Preparing Your Drug for Clinical Success: Strategies and Considerations
Summary: View this webinar to learn about the key considerations for transitioning a molecule from discovery through clinical studies.
Based on Exclusive Survey: Bioavailability Enhancement – Industry Insights, Key Challenges & Advanced Development Solutions
Summary: In this webinar, experts present the exclusive survey findings and introduce innovative scalable drug delivery technologies proven to address the industry’s growing need for improving solubility and enhancing bioavailability.
Spray Drying for Bioavailability Enhancement
Summary: The use of spray drying to manufacture amorphous dispersions is continuing to grow due to the number of drug candidates exhibiting poor solubility. Nearly 40% of the new chemical…
How to Effectively Work with a Development Partner – From a Consultant Standpoint
Summary: Hear from experienced industry colleagues on the latest tips that will help your clients avoid critical pitfalls in early development of their drugs to best leverage CDMO…
Strategies for Flexible Manufacturing
Summary: Pharmaceutical and biotechnology companies approach external development and manufacturing partners for solutions for their product’s specific needs. New products are increasingly…
Proven Bioavailability Enhancement Solutions for Scalable and Robust Products
Summary: Lipid formulation and spray-dried dispersions are widely used, and proven technologies to overcome bioavailability challenges for poorly soluble molecules. For selecting the…
How to Accelerate Early Drug Development in Oncology For Small Molecules and Biologics
Summary: Get an insight into what it takes to move a pre-clinical drug candidate to a Phase 1 clinical trial. The presentations will provide guidance on non-clinical and regulatory considerations…
Spray-Drying Process for Scale up and Commercialization
Summary: The use of spray drying to manufacture amorphous dispersions is continuing to grow due to the number of drug candidates exhibiting poor solubility. In a recent Pharmaceutical…
Prepare Your Clients for Success: Tips and Strategies to Avoid Dangerous Pitfalls in Consulting
Summary: Determining a client’s primary goal is critical to guiding them through the development of their asset. Additionally, their primary focus will impact the strategy used to develop…
Rapid Developability Assessment of Early Phase Molecules: Parallel Screening of Enabling Technologies and Use of PBPK Modeling
Summary: Achieving success in early development is essential in progressing to your molecule’s next milestone. While solving solubility is a major hurdle to overcome in early development…
All Offerings
Summary: Catalyst + Talent. Our name combines these ideas. From drug and biologic development to delivery technologies and supply solutions, we are the catalyst for your…
Planning for Successful Product Launches
Summary: There has been increased focus and efforts on developing treatments for diseases with smaller patient populations, diseases for which there are no currently approved treatments…
A Roadmap for Early Development to Commercial Manufacturing
Summary: A key hurdle for any drug development program is bringing the drug to clinical studies. Astute companies strategize past this milestone and plan for clinical and regulatory success.
Placing Patients at the Center of Drug Design
Summary: Patient centricity has always been at the heart of the pharmaceutical industry. With rising costs of drugs and healthcare, there has been an increased focus on the topic. Poor patient acceptance and…
Regulatory Support
Summary: Our regulatory team completes over 150 agency submissions each year, supporting all stages of the product lifecycle. We assign a dedicated…
How to Effectively Work with a Development Partner – From a Consultant Standpoint
Summary: Determining a client’s primary goal is critical to guiding them through the development of their asset. Three experienced industry colleagues recently presented on the latest tips…
Zydis® Oral Fast Dissolve | Why Catalent?
Summary: The Zydis® ODT fast-dissolve formulation, is a unique, freeze-dried oral solid dosage form that disperses instantly in the mouth – no water required. With more than 20 products launched…
Reliably Supplied | Why Catalent?
Summary: We have the technology and expertise to take your product from design, to clinical trial, to plant, to pharmacy. Our global network of facilities can provide scalable, cost-effective…
Catalent Zydis Fast Dissolve
Summary: Zydis®, our proprietary fast-dissolve technology, is a unique, freeze-dried oral solid dosage form that disperses instantly in the mouth – no water required. With more than…
Catalent in 30 Seconds
Summary: With over 80 years serving the industry, Catalent is the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products….
Optimal Drug Delivery Technologies. Better Treatments.
Summary: We are your catalyst for creating better treatments. Our deep expertise in drug development, delivery and supply can help improve the bioavailability of your compound, enhance therapeutic profiles…
Catalent Corporate Overview
Summary: Catalent is the global leader in development, delivery, and supply for pharmaceuticals, biologics, and consumer health products. Integrated analytical and clinical supply services support to…
Unlock Your Molecules Potential with Catalent
Summary: Your molecule has so much potential, we share the passion to unlock it through extensive expertise and superior formulation technologies. Learn how we have optimized thousands…
Bring Pharma, Biopharma and Consumer Health Products to Market with Catalent
Summary: A short video on how Catalent can help you develop, deliver, supply better treatments. Whether it is Pharmaceuticals, Biopharmaceuticals, Over-the-Counter, Nutritionals or Beauty Care and Cosmetics, we can…
OptiForm® Solution Suite – Fast Track Early Development | Catalent in 90 Seconds
Summary: Learn about a Fast, Flexible and Fact-based path for your molecule to progress from late-stage discovery to phase I.
Zydis® ODT – Real World Solutions for Patients
Summary: Zydis® ODT is an orally dissolving tablet formulated as for fast dissolve that requires little to no water when taking the medication. It provides an ideal dosing solution when dealing…
Career Development at Catalent
Summary: Catalent offers employees numerous opportunities for development and career progression. Hear more about what our team has to say about how Catalent supports their…
Product Development Careers at Catalent
Summary: Members of our product development eam gain unparalleled experience working on several products using multiple technologies. Hear what it’s like to work…
Zydis® ODT Consistently Offers Effective Solutions for Sublingual Allergy Immunotherapy
Summary: ALK-Abelló A/S is a Denmark-based pharmaceutical company that specializes in the development of immunotherapy products for the treatment of respiratory allergies. ALK partnered with Catalent for…
Beyond HPLCs: Advanced Analytical Tools for the Development and Analysis of Drug Products
Summary: Advanced analytical techniques can provide timely insights into a product’s stability, performance, and composition. Download this webinar to get expert insights on the applications of analytical techniques to help answer various questions…
An Integrated Approach to Spray Drying – From Scale-up to Manufacturing
Summary: The use of spray drying to manufacture amorphous dispersions is continuing to grow due to the number of drug candidates exhibiting poor solubility. Nearly 40% of the new chemical entities (NCEs) screened by pharmaceutical…
Unlock Industry Perspectives on the Advantages and Challenges of Developing Advanced Dosage Forms
Summary: Watch the webinar to learn about the tools and technologies for creating dosage forms such as orally disintegrating tablets (ODTs), multi-particulates, and modified release formulations.
Strategies To Develop Lipid-Based Drug Delivery Systems And Oral Dosage Forms
Summary: Liquid-filled capsules (LFC) are the primary delivery platform for oral delivery of lipid formulations which includes both softgels and liquid-filled hard capsules. Liquid-in-bottle is…
Overcoming Manufacturing Challenges For Accelerated Drug Development
Summary: It has been reported that surveys of migraine patients have revealed a preference for oral medications with a rapid onset of action that leads to a resolution of their symptoms. Due to the random nature of migraine attacks..
ZYDIS® ODT Unlocks a Patient Preference for Rapid Onset in the Treatment of Migraine
Summary: It has been reported that surveys of migraine patients have revealed a preference for oral medications with a rapid onset of action that leads to a resolution of their symptoms. Due to the random nature of migraine attacks..
Why Do New Therapies Succeed Or Fail In The Marketplace?
How can decisions made during the preclinical phase of drug development increase the chances of a product’s eventual success in a difficult marketplace?
Patient-Focused Drug Design – A View From The R&D Front Lines
Summary: Incorporation of patient-focused drug design principles is increasingly becoming essential to ensure that a new drug is commercially successful and delivers the best patient outcomes.
Lipid Workshop Part 1: Early Development With Lipids
Get insights on using lipid systems during early development to achieve successful formulation and patient outcomes
AAPS 2015 Posters
Catalent’s experts presented technical posters on advanced drug design, discovery, development, delivery, packaging and scale-up. Click here to download [Part 1] of the 2015 AAPS posters Click here to…
Designing Complex Release Oral Solids
Controlled and Modified Release dosage form can improve patient experience.
Elemental Impurities- Guidelines, Testing And Assessments
This eBook published by Pharmaceutical Technology provides an overview of the regulatory landscape related to elemental impurities testing, discusses the challenges of implementing ICH Q3D guidelines …
Commercial Scale-Up On Fluid Bed Wurster Coating
You will learn about a pharmaceutical company who was interested in scaling-up a multi-particulate, modified-release product to a commercial scale using fluid bed bottom-spray (Wurster) coating.
Softgel Technology For Fast-Tracked Development Programs
Summary: Given the accelerated timelines associated with expedited programs, lipid-based drug formulations, encapsulated in softgel capsules, provide an attractive option for addressing the challenges…
De-Risk Your Early Phase Programs
Lipid based drug delivery systems (LBDDS) are the most studied and understood bioavailability enhancing solutions
Elemental Impurities- Guidelines, Testing and Assessments
Testing for elemental impurities in pharmaceuticals is a key risk assessment activity. This eBook published by Pharmaceutical Technology provides an overview…
A View From The R&D Front Lines
Incorporation of patient-focused drug design principles is increasingly becoming essential to ensure that a new drug is commercially successful and delivers the best patient outcomes.
The Product Development Superhighway
Pharmaceutical and biotechnology companies value streamlined services from early-phase development to clinical supply services to commercialization.
Formulation Development for Scalability
Lipid formulation and spray-dried dispersions are widely used, and proven technologies to overcome bioavailability challenges for poorly soluble molecules.
Commonly Asked Questions About Elemental Impurities
Read the latest article published by Pharmaceutical Technology giving an overview of elemental impurities testing and elemental impurities risk assessment process.
Exploring Barriers and Facilitators to Drug Launch Success
Understand why new therapies fail or succeed in the market place and learn when and how to apply advanced technologies to help increase the chance of success
Value Creation in the Early Phase
Strategies companies can use to succeed in both advancing their candidates and attracting investors
Quality by Design Approach to Analytical Method Optimization
Quality by Design (QbD) is well established in the pharmaceutical industry for manufacturing processes, including active pharmaceutical ingredients and drug products.
Streamline Early Drug Development
How to create a development strategy that bridges gaps earlier in the process to make the transition smoother.
The Role of Roller Compaction in Dose Design
Roller compaction is a popular dry granulation process with some significant advantages over wet granulation processes.
Phase Appropriate Stability Studies
Stability is a critical quality attribute of pharmaceutical products
Formulation Design in Oral GLP Toxicology Studies
Read this article and learn about focus areas in the early drug development process that are critical for a successful toxicology study.
Scale-up of Wurster Process
Learn more about Wurster Process at Catalent Winchester.
Commercial Scale-Up on Fluid Bed Wurster Coating
Read this case study on commercial scale-up on fluid bed wurster coating.
Dysphagia Dose Design
Gain more knowledge on dysphagia, which is one of the major factors affecting medication adherence and proper medication administration.
PBPK Modeling and Other Strategies for Early Phase Success
Leveraging knowledge about an API’s physiochemical properties from preformulation and formulation studies increases the chances of early-phase success.
Overcoming Technology Transfer Challenges
The key to a successful tech transfer is for the vendor and the contract manufacturer to anticipate the challenges and come up with a game plan for the solutions to potential challenges.
Risk Assessment & Test Requirements for Elemental Impurities
Selecting the best risk assessment and analytical testing strategy is key to successful compliance with the new regulations.
Best Practices for Identifying Development Candidates
The use of Pre-clinical tools to study pharmacokinetics, choose a lead drug candidate and move that product into development.
Putting The Patient First When Manufacturing OSD Forms
Expert insights on ODT challenges and solutions from European Pharma Manufacturing.
Technical Guide for Solid Dispersion Development
Get the steps involved in the development and manufacturing of an ASD via the spray drying process.
The Formulation Complex
Tips and advice on overcoming the most common formulation mishaps and why beginning with the end in mind is crucial.
From Candidate to Clinic
Strategies to Select, Assess, Formulate, and Deliver the Right Drug Candidate in the Early Phase.
Dose Selection Using Preclinical PK Modeling
How pre-clinical tools used in the industry to study pharmacokinetics are used to guide the development of new chemical entities (NCEs).
Design & Formulation for GLP Toxicology Studies
Evaluate critical areas in the drug development process to help ensure a successful toxicology study.
Review and Analysis of FDA Approved Drugs Using Lipids
A review and quantitative analysis of the molecular properties of approved drugs formulated as lipid systems
Bioavailability Enhancement Through Spray Dried Dispersions
The key spray dried dispersion (SDD) development considerations to enhance and sustain in-vivo drug solubility.
Bioavailability Enhancement through Spray Dried Dispersions
The key spray dried dispersion (SDD) development considerations to enhance and sustain in-vivo drug solubility.
Designing Complex Release Oral Solids
Controlled and Modified Release dosage form can improve patient experience.
Tech Talks with Catalent – Spray Drying Technology
Successful spray drying process for clinical and commercial production.
Smart Drug Development & Design from Candidate to Phase I
Key considerations for transitioning a molecule from discovery to phase 1 readiness
Data-Driven Approach to Overcome Bioavailability Challenges
Unbiased & data-driven approach to select bioavailability enhancement technology.
Solid Dose Trends
How the industry’s most stable drug form is innovating and evolving to stay relevant.
Formulating Candidates with Bioavailability Issues
How formulation screening early in the process can reduce development timelines.
Improve Patient Experience and Therapeutic Outcomes
Advanced formulation and drug delivery technologies for patient-centric drug design.
Developing Oral Dosage Forms
Agnostic & data-driven approach for early stages to find optimal formulation technology
Orally Disintegrating Tablets- A Patient-Centric Dosage Form
Discover how orally disintegrating tablets (ODTs) can be both patient friendly and offer numerous formulation advantages.
Oral Delivery of Macromolecule Drugs for Localized Treatment
Latest formulation approaches on enabling oral route for macromolecule drugs for local treatment.
Early-Phase Pharmaceutical Development Strategies
Insight on early development, characterizing solid state forms and first-in-human strategies.
Preclinical & First-in-Man Drug Development Strategies
Methods for developing a sound, phase-appropriate formulation for early development.
ODT: A Patient-Centric Dosage Form
Discover new developments in ODT technology including delivery of peptides and vaccines.
Improve Your Phase I Success Rate
A parallel formulation feasibility assessment approach to enhance bioavailability.
Overcome Barriers to Non-invasive Delivery Of Macromolecules
Innovative, integrated approach to rapidly screen biomolecules potential for oral delivery.
AAPS 2016 Presentations
Discover the latest solutions and advancement in drug delivery technologies.
A Dosage Form Designed for Difficult Patient Populations
Explore how orally disintegrating tablets (ODTs) provide an alternative to overcome several challenges.
A Holistic Approach for Drug Development and Delivery
How can a patient-centric outlook help scientists tackle the key challenges of early drug development.
Unlock Oral Delivery Potential for Macromolecules
Effectively evaluate the potential of peptides and macromolecules for oral delivery.
Innovative Drug Delivery Technologies for Better Treatments
Better patient treatments fueled by innovations in lipid formulations.
How Parallel Development with Proven Technologies Improves
Efficiently and rapidly overcome complex bioavailability challenges for early stage molecules.
Enhance Bioavailability with Parallel Screening Technologies
Characterize molecules, apply right prediction model, & select ideal delivery technology.
The Versatile Orodispersable Tablet (ODT) Technology
ODT platform ideal for sublingual delivery of proteins, peptides & vaccines.
Oral Dose Development of Macromolecules
Discover new approach to optimize oral dose development for macromolecules.
Optimal Formulation Technology for Better Patient Treatment
Strategies for oral formulation selection which can lower attrition rates and more.
Graphicaps™ Inline Printing
Differentiate products at the unit dose level & deliver a more recognizable product.
The Next Generation ODT
New developments in ODT technology, including new ways to administer peptides & vaccines.
Parallel Screening for Non-Invasive Macromolecule Delivery
Integrated solutions to rapidly screen biomolecules potential for non-invasive delivery route.
Strategies To Overcome Development Challenges
Address development challenges early on and improve a drug’s path to market.
Accelerate Development for Challenging Compounds
Leverage solid dispersion & particle size reduction technology to enhance bioavailability.
Optimizing API Properties And Formulation
Utilize particle size reduction and formulation technologies to optimize the API.
Novel Technologies To Deliver Oral Oncology Therapies
Select optimal formulation technology to enhance therapeutic performance & patient experience.
Create Effective Fast-Dissolving Oral Formulations
Successfully manufacture oral dosage forms that disperse within 3 seconds & are enjoyable.
The Medicine Maker – The Toolbox of 2025
Overcome therapeutic challenges and be prepared for years to come.
Oral Formulation Strategies and Technologies
Oral dose development with optimal therapeutic performance.
Bringing a Small Molecule to Clinic
Transition from preliminary formulation to commercial drug launch, quickly & cost-effectively.
Pharmaceutical Abuse Deterrent Capsule Formulations
Develop liquid capsule fill formulations that are mitigated to prevent abuse.
New Approaches for Macromolecule Oral Delivery
The toolkit of technologies based upon lipid-based drug delivery systems.
OptiGel Bio Enables Delivery of Synthetic Oligosaccharides
Macromolecules can potentially be converted from injectable to oral drug delivery.