Strategies To Develop Lipid-Based Drug Delivery Systems And Oral Dosage Forms
Summary: Liquid-filled capsules (LFC) are the primary delivery platform for oral delivery of lipid formulations which includes both softgels and liquid-filled hard capsules. Liquid-in-bottle is…
Overcoming Manufacturing Challenges For Accelerated Drug Development
Summary: It has been reported that surveys of migraine patients have revealed a preference for oral medications with a rapid onset of action that leads to a resolution of their symptoms. Due to the random nature of migraine attacks..
ZYDIS® ODT Unlocks a Patient Preference for Rapid Onset in the Treatment of Migraine
Summary: It has been reported that surveys of migraine patients have revealed a preference for oral medications with a rapid onset of action that leads to a resolution of their symptoms. Due to the random nature of migraine attacks..
Why Do New Therapies Succeed Or Fail In The Marketplace?
How can decisions made during the preclinical phase of drug development increase the chances of a product’s eventual success in a difficult marketplace?
Patient-Focused Drug Design – A View From The R&D Front Lines
Patient-Focused Drug Design – A View From The R&D Front Lines Summary: Incorporation of patient-focused drug design principles is increasingly becoming essential to ensure that a new drug is commercially successful and delivers the best patient...
Lipid Workshop Part 1: Early Development With Lipids
Lipid Workshop Part 1: Early Development With Lipids Summary: There is a need to match the right formulation approach to the drug compound in early development but most of the formulation approaches are not optimized for patient outcomes! Download the...
AAPS 2015 Posters
AAPS 2015 Posters Summary: The 2015 AAPS Annual Meeting and Exposition is a dynamic international forum for the exchange of knowledge among scientists to enhance their contributions to public health. Catalent's experts presented technical posters on...
Designing Complex Release Oral Solids
Controlled and Modified Release dosage form can improve patient experience.
Elemental Impurities- Guidelines, Testing And Assessments
Elemental Impurities- Guidelines, Testing And Assessments Summary: Testing for elemental impurities in pharmaceuticals is a key risk assessment activity. This eBook published by Pharmaceutical Technology provides an overview of the regulatory...
Commercial Scale-Up On Fluid Bed Wurster Coating
Commercial Scale-Up On Fluid Bed Wurster Coating Summary: Read this case study on commercial scale-up on fluid bed wurster coating. You will learn about a pharmaceutical company who was interested in scaling-up a multi-particulate, modified-release product...
Better Treatments By Design
Better Treatments By Design Summary: To be successful, new treatments require real-world outcomes for you, your stakeholders, and most importantly the patients. With the Better Treatments by Design™ process, Catalent aims to achieve optimal outcomes for...
Softgel Technology For Fast-Tracked Development Programs
Softgel Technology For Fast-Tracked Development Programs Summary: Given the accelerated timelines associated with expedited programs, lipid-based drug formulations, encapsulated in softgel capsules, provide an attractive option for addressing the...
De-Risk Your Early Phase Programs
Lipid based drug delivery systems (LBDDS) are the most studied and understood bioavailability enhancing solutions
Elemental Impurities- Guidelines, Testing and Assessments
Testing for elemental impurities in pharmaceuticals is a key risk assessment activity. This eBook published by Pharmaceutical Technology provides an overview…
A View From The R&D Front Lines
Incorporation of patient-focused drug design principles is increasingly becoming essential to ensure that a new drug is commercially successful and delivers the best patient outcomes.
The Product Development Superhighway
Pharmaceutical and biotechnology companies value streamlined services from early-phase development to clinical supply services to commercialization.
Formulation Development for Scalability
Lipid formulation and spray-dried dispersions are widely used, and proven technologies to overcome bioavailability challenges for poorly soluble molecules.
Commonly Asked Questions About Elemental Impurities
Read the latest article published by Pharmaceutical Technology giving an overview of elemental impurities testing and elemental impurities risk assessment process.
Exploring Barriers and Facilitators to Drug Launch Success
Understand why new therapies fail or succeed in the market place and learn when and how to apply advanced technologies to help increase the chance of success
Value Creation in the Early Phase
Strategies companies can use to succeed in both advancing their candidates and attracting investors
Quality by Design Approach to Analytical Method Optimization
Quality by Design (QbD) is well established in the pharmaceutical industry for manufacturing processes, including active pharmaceutical ingredients and drug products.
Streamline Early Drug Development
How to create a development strategy that bridges gaps earlier in the process to make the transition smoother.
The Role of Roller Compaction in Dose Design
Roller compaction is a popular dry granulation process with some significant advantages over wet granulation processes.
Phase Appropriate Stability Studies
Stability is a critical quality attribute of pharmaceutical products
Formulation Design in Oral GLP Toxicology Studies
Read this article and learn about focus areas in the early drug development process that are critical for a successful toxicology study.
Scale-up of Wurster Process
Learn more about Wurster Process at Catalent Winchester.
Commercial Scale-Up on Fluid Bed Wurster Coating
Read this case study on commercial scale-up on fluid bed wurster coating.
Dysphagia Dose Design
Gain more knowledge on dysphagia, which is one of the major factors affecting medication adherence and proper medication administration.
PBPK Modeling and Other Strategies for Early Phase Success
Leveraging knowledge about an API’s physiochemical properties from preformulation and formulation studies increases the chances of early-phase success.
Overcoming Technology Transfer Challenges
The key to a successful tech transfer is for the vendor and the contract manufacturer to anticipate the challenges and come up with a game plan for the solutions to potential challenges.
Risk Assessment & Test Requirements for Elemental Impurities
Selecting the best risk assessment and analytical testing strategy is key to successful compliance with the new regulations.
Best Practices for Identifying Development Candidates
The use of Pre-clinical tools to study pharmacokinetics, choose a lead drug candidate and move that product into development.
Identify Unknown Leachable Species from BFS Vials
Identifying and verifying an unknown leachable through structural elucidation, synthesis and mass spectral confirmation.
Putting The Patient First When Manufacturing OSD Forms
Expert insights on ODT challenges and solutions from European Pharma Manufacturing.
Technical Guide for Solid Dispersion Development
Get the steps involved in the development and manufacturing of an ASD via the spray drying process.
The Formulation Complex
Tips and advice on overcoming the most common formulation mishaps and why beginning with the end in mind is crucial.
From Candidate to Clinic
Strategies to Select, Assess, Formulate, and Deliver the Right Drug Candidate in the Early Phase.
Dose Selection Using Preclinical PK Modeling
How pre-clinical tools used in the industry to study pharmacokinetics are used to guide the development of new chemical entities (NCEs).
Design & Formulation for GLP Toxicology Studies
Evaluate critical areas in the drug development process to help ensure a successful toxicology study.
Review and Analysis of FDA Approved Drugs Using Lipids
A review and quantitative analysis of the molecular properties of approved drugs formulated as lipid systems
Bioavailability Enhancement Through Spray Dried Dispersions
The key spray dried dispersion (SDD) development considerations to enhance and sustain in-vivo drug solubility.
Bioavailability Enhancement through Spray Dried Dispersions
The key spray dried dispersion (SDD) development considerations to enhance and sustain in-vivo drug solubility.
Designing Complex Release Oral Solids
Controlled and Modified Release dosage form can improve patient experience.
Tech Talks with Catalent – Spray Drying Technology
Successful spray drying process for clinical and commercial production.
Smart Drug Development & Design from Candidate to Phase I
Key considerations for transitioning a molecule from discovery to phase 1 readiness
Data-Driven Approach to Overcome Bioavailability Challenges
Unbiased & data-driven approach to select bioavailability enhancement technology.
Solid Dose Trends
How the industry’s most stable drug form is innovating and evolving to stay relevant.
Formulating Candidates with Bioavailability Issues
How formulation screening early in the process can reduce development timelines.
Improve Patient Experience and Therapeutic Outcomes
Advanced formulation and drug delivery technologies for patient-centric drug design.
Developing Oral Dosage Forms
Agnostic & data-driven approach for early stages to find optimal formulation technology
Accelerate Your Early Drug Development Journey
Learn how to move from the bench to the clinic quickly using advanced technologies
Orally Disintegrating Tablets- A Patient-Centric Dosage Form
Discover how orally disintegrating tablets (ODTs) can be both patient friendly and offer numerous formulation advantages.
Oral Delivery of Macromolecule Drugs for Localized Treatment
Latest formulation approaches on enabling oral route for macromolecule drugs for local treatment.
Early-Phase Pharmaceutical Development Strategies
Insight on early development, characterizing solid state forms and first-in-human strategies.
Preclinical & First-in-Man Drug Development Strategies
Methods for developing a sound, phase-appropriate formulation for early development.
ODT: A Patient-Centric Dosage Form
Discover new developments in ODT technology including delivery of peptides and vaccines.
Improve Your Phase I Success Rate
A parallel formulation feasibility assessment approach to enhance bioavailability.
Overcome Barriers to Non-invasive Delivery Of Macromolecules
Innovative, integrated approach to rapidly screen biomolecules potential for oral delivery.
AAPS 2016 Presentations
Discover the latest solutions and advancement in drug delivery technologies.
A Dosage Form Designed for Difficult Patient Populations
Explore how orally disintegrating tablets (ODTs) provide an alternative to overcome several challenges.
A Holistic Approach for Drug Development and Delivery
How can a patient-centric outlook help scientists tackle the key challenges of early drug development.
Unlock Oral Delivery Potential for Macromolecules
Effectively evaluate the potential of peptides and macromolecules for oral delivery.
Innovative Drug Delivery Technologies for Better Treatments
Better patient treatments fueled by innovations in lipid formulations.
About Us: Catalent Corporate Brochure
We are helping innovators develop, deliver & supply superior products improving people’s lives.
How Parallel Development with Proven Technologies Improves
Efficiently and rapidly overcome complex bioavailability challenges for early stage molecules.
Enhance Bioavailability with Parallel Screening Technologies
Characterize molecules, apply right prediction model, & select ideal delivery technology.
The Versatile Orodispersable Tablet (ODT) Technology
ODT platform ideal for sublingual delivery of proteins, peptides & vaccines.
Oral Dose Development of Macromolecules
Discover new approach to optimize oral dose development for macromolecules.
Optimal Formulation Technology for Better Patient Treatment
Strategies for oral formulation selection which can lower attrition rates and more.
Graphicaps™ Inline Printing
Differentiate products at the unit dose level & deliver a more recognizable product.
The Next Generation ODT
New developments in ODT technology, including new ways to administer peptides & vaccines.
Parallel Screening for Non-Invasive Macromolecule Delivery
Integrated solutions to rapidly screen biomolecules potential for non-invasive delivery route.
Strategies To Overcome Development Challenges
Address development challenges early on and improve a drug’s path to market.
Accelerate Development for Challenging Compounds
Leverage solid dispersion & particle size reduction technology to enhance bioavailability.
Optimizing API Properties And Formulation
Utilize particle size reduction and formulation technologies to optimize the API.
Novel Technologies To Deliver Oral Oncology Therapies
Select optimal formulation technology to enhance therapeutic performance & patient experience.
Create Effective Fast-Dissolving Oral Formulations
Successfully manufacture oral dosage forms that disperse within 3 seconds & are enjoyable.
The Medicine Maker – Delivering Change
The future of non-invasive delivery technologies for large molecules.
The Medicine Maker – The Toolbox of 2025
Overcome therapeutic challenges and be prepared for years to come.
Oral Formulation Strategies and Technologies
Oral dose development with optimal therapeutic performance.
Bringing a Small Molecule to Clinic
Transition from preliminary formulation to commercial drug launch, quickly & cost-effectively.
Pharmaceutical Abuse Deterrent Capsule Formulations
Develop liquid capsule fill formulations that are mitigated to prevent abuse.
New Approaches for Macromolecule Oral Delivery
The toolkit of technologies based upon lipid-based drug delivery systems.
OptiGel Bio Enables Delivery of Synthetic Oligosaccharides
Macromolecules can potentially be converted from injectable to oral drug delivery.