Roller Compaction: New Trends, Challenges and Solutions
This article discusses why roller compaction is a robust option when developing a tablet or capsule formulation.
Strategies for De-risking Early-Phase Oral Small Molecule Drug Development
Summary: Characterize lead molecules and develop the best pathway to bring them to Phase I studies and beyond.
Partnering for Success: Strategies to Mitigate Common Pitfalls in Early Drug Development
Summary: Thousands of drug candidates are abandoned annually due to solubility and bioavailability issues, but advanced formulation technologies can profoundly impact how a drug compound…
Analyzing Product Formulation Using Raman Spectroscopy
Comparing the dissolution rates and pellet structure of branded Sporanox® with three similar generic products, raman spectroscopy revealed recrystallizing API slowed the dissolution rate.
NMR and Mass Spectrometry in Pharmaceutical Development
Nuclear Magnetic Resonance spectroscopy and Mass Spectrometry are powerful techniques for the characterization and quantification of compounds.