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Intranasal Drug Delivery-Identifying Challenges and New Product Opportunities

Summary: The drug delivery market continues to evolve with novel solutions being explored, beyond conventional oral dosage forms. The intranasal delivery route is frequently chosen for the local treatment of allergic rhinitis, nasal congestion and cold symptoms. However, intranasal delivery is emerging as an alternative route of systemic drug delivery for a variety of indications such as migraine, seizures, breakthrough pain and opioid overdose and more.

Watch this webinar to learn about the challenges, opportunities and advantages of intranasal drug delivery. An overview of the anatomy and physiology of the nasal cavity will provide an appreciation of the rationale for intranasal drug delivery, and how this influences key product development considerations. Experts will also discuss the utility of physiological-based pharmacokinetic (PBPK) modeling and simulation, and assessment of API physicochemical properties as predictors of the extent of systemic absorption following intranasal administration. The complex interplay between product attributes, drug exposure and manufacturing processes will also be addressed.

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